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CARMA1 / CARD11 Antibody

Catalog # Availability Size / Price Inquiry
APR02671G 50 μl / $495

CARMA1 / CARD11 Antibody

Brand

Leading Biology

Catalog Number

APR02671G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CARMA1 / CARD11 Antibody.

Molecular Weight

133kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Membrane raft. Note=Colocalized with DPP4 in membrane rafts

Host

Rabbit

Species Reactivity

Human

Target

Human CARD11. Predicted cross-reactivity based on amino acid sequence homology: mouse (96%), bovine (98%).

Symbol

CARMA1

GeneID

UniProt ID

Function

Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.

Summary

Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (10 μg/ml), WB (1:500-1:3000),

Images

Sample (30 ug of whole cell lysate).

Anti-CARD11 antibody IHC of human cerebellum.

Specification

Quantity

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