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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ANAPC5 / APC5 Antibody (Internal)

ANAPC5 / APC5 Antibody (Internal)

Catalog # Availability Size / Price Inquiry
APR02654G 50 μg / $495

ANAPC5 / APC5 Antibody (Internal)

Brand

Leading Biology

Catalog Number

APR02654G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ANAPC5 / APC5 Antibody (Internal).

Molecular Weight

85kDa

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Human ANAPC5

Symbol

APC5

GeneID

UniProt ID

Function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Summary

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IHC-P (5 μg/ml), WB (1-2 μg/ml),

Images

Immunofluorescence of APC5 in rat kidney tissue with APC5 antibody at 20 ug/ml.

Western blot of APC5 in human kidney tissue lysate with APC5 antibody at (A) 1 and (B) 2 ug/ml.

Anti-ANAPC5 / APC5 antibody IHC of human small intestine.

Specification

Quantity

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