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CD32B Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APG01113G 50 μg / $495

CD32B Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APG01113G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD32B Antibody (C-Terminus).

Molecular Weight

34kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

Host

Goat

Species Reactivity

Human

Target

Human FCGR2B / CD32B. This antibody is expected to recognise all reported isoforms (NP_001002273.1; NP_001002274.1; NP_001002275.1; NP_003992.3; NP_001177757.1).

Symbol

CD32, FCG2, IGFR2

GeneID

UniProt ID

Function

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Summary

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:16000), IHC-P (3.75 μg/ml), WB (0.3-1 μg/ml)

Images

Antibody (0.3 ug/ml) staining of K562 lysate (35 ug protein in RIPA buffer).

Anti-CD32B antibody IHC of human liver.

Specification

Quantity

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