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F12 / Factor XII Antibody

Catalog # Availability Size / Price Inquiry
APS00007G 100 μg / $495

F12 / Factor XII Antibody

Brand

Leading Biology

Catalog Number

APS00007G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality F12 / Factor XII Antibody.

Molecular Weight

68kDa

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Sheep

Species Reactivity

Human

Target

Recognises Factor XII

GeneID

UniProt ID

Function

Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta- factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.

Summary

Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta- factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

IHC-P (5 μg/ml)

Images

Anti-F12 / Factor XII antibody IHC of human liver.

Specification

Quantity

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