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F7 / Factor VII Antibody

Catalog # Availability Size / Price Inquiry
APR02620G 50 μl / $495

F7 / Factor VII Antibody

Brand

Leading Biology

Catalog Number

APR02620G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality F7 / Factor VII Antibody.

Molecular Weight

52kDa

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse

Target

Human and mouse F7. Predicted cross-reactivity based on amino acid sequence homology: monkey (91%).

GeneID

UniProt ID

Function

Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.

Summary

Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (10 μg/ml), WB (1:500-1:3000),

Images

Sample(30 g of whole cell lysate). A: H1299. 7.5% SDS PAGE. F7 antibody diluted at 1:500.

Sample (30 ug of whole cell lysate). A: NIH-3T3. 10% SDS PAGE. F7 antibody diluted at 1:1000.

Specification

Quantity

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