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POU5F1 / OCT4 Antibody

Catalog # Availability Size / Price Inquiry
APR02616G 50 μl / $495

POU5F1 / OCT4 Antibody

Brand

Leading Biology

Catalog Number

APR02616G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality POU5F1 / OCT4 Antibody.

Molecular Weight

39kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Expressed in a diffuse and slightly punctuate pattern

Host

Rabbit

Species Reactivity

Human

Target

Human OCT3/4. Predicted cross-reactivity based on amino acid sequence homology: rabbit (85%), bovine (85%), pig (88%), monkey (97%).

Symbol

OCT3, OCT4, OTF3

GeneID

UniProt ID

Function

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Summary

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, ICC, Flo

Dilution

ICC (1:100-1:200), IF (1:100-1:200), IHC-P (10 μg/ml), WB (1:500-1:3000) ,

Images

Immunofluorescence of paraformaldehyde-fixed human embryonic stem cell, using OCT3/4 antibody at...

Anti-POU5F1 / OCT4 antibody IHC of human testis.

Specification

Quantity

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