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CD14 Antibody (Internal)

Catalog # Availability Size / Price Inquiry
APG01043G 50 μg / $495

CD14 Antibody (Internal)

Brand

Leading Biology

Catalog Number

APG01043G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD14 Antibody (Internal).

Molecular Weight

40kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor.

Host

Goat

Species Reactivity

Human

Target

Human CD14.

GeneID

UniProt ID

Function

In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

Summary

In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:128000), IHC-P (4 μg/ml), WB (1-3 μg/ml)

Images

Anti-CD14 antibody IHC of human spleen.

Specification

Quantity

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