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TP73 / p73 Antibody (aa75-125)

Catalog # Availability Size / Price Inquiry
APR02480G 50 μg / $495

TP73 / p73 Antibody (aa75-125)

Brand

Leading Biology

Catalog Number

APR02480G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TP73 / p73 Antibody (aa75-125).

Molecular Weight

70kDa

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Accumulates in the nucleus in response to DNA damage

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Hamster, Monkey, Bovine, Dog

Target

A portion of amino acids 75-125 of human p73 protein was used as the immunogen.

Symbol

P73

GeneID

UniProt ID

Function

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Summary

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (5 μg/ml), WB (1-3 μg/ml),

Images

Western blot of p73 in A) transfected cell lysate and B) HeLa cell lysate using antibody at 1 ug/ml.

Anti-p73 antibody IHC of human breast.

Specification

Quantity

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