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BAFF Antibody (aa254-269)

Catalog # Availability Size / Price Inquiry
APR02478G 50 μg / $495

BAFF Antibody (aa254-269)

Brand

Leading Biology

Catalog Number

APR02478G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BAFF Antibody (aa254-269).

Molecular Weight

31kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Target

A C-terminal peptide corresponding to amino acids 254-269 of human BLyS.

Symbol

BAFF, BLYS, TALL1, TNFSF20, ZTNF4

GeneID

UniProt ID

Function

Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.

Summary

Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (10 μg/ml), WB (0.5-2 μg/ml),

Images

Western blot of BAFF/BLyS in mouse and human cell lysates.

Specification

Quantity

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