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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TP53BP1 / 53BP1 Antibody (C-Terminus)

TP53BP1 / 53BP1 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR02427G 50 μl / $495

TP53BP1 / 53BP1 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR02427G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TP53BP1 / 53BP1 Antibody (C-Terminus).

Molecular Weight

214kDa

Cellular Localization

Antigen Cellular Localization: Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores. Both nuclear and cytoplasmic in some cells. Recruited to sites of DNA damage, such as double stand breaks. H4K20me2 is required for efficient localization to double strand breaks and removal of proteins that have a high affinity for H4K20me2 such as L3MBTL1 and KDM4A is needed

Host

Rabbit

Species Reactivity

Human

Target

Human 53BP1

GeneID

UniProt ID

Function

Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53- mediated transcriptional activation.

Summary

Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53- mediated transcriptional activation.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (5 μg/ml)

Images

Anti-TP53BP1 / 53BP1 antibody IHC of human skeletal muscle.

Specification

Quantity

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