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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HSP90AB1 / HSP90 Alpha B1 Antibody (Ser254)

HSP90AB1 / HSP90 Alpha B1 Antibody (Ser254)

Catalog # Availability Size / Price Inquiry
APR02405G 50 μg / $495

HSP90AB1 / HSP90 Alpha B1 Antibody (Ser254)

Brand

Leading Biology

Catalog Number

APR02405G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HSP90AB1 / HSP90 Alpha B1 Antibody (Ser254).

Molecular Weight

83kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Amino acids surrounding Ser 254 of human HSP90AB1

Symbol

HSP90B, HSPC2, HSPCB

GeneID

UniProt ID

Function

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Summary

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF

Dilution

IHC-P (10 μg/ml)

Images

Western blot of extracts from HeLa and A2780 cells using HSP90B(Ab-254) antibody.

Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic staining using...

Anti-HSP90AB1 antibody IHC of human spleen.

Specification

Quantity

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