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CREB1 / CREB Antibody (Ser133)

Catalog # Availability Size / Price Inquiry
APR02401G 50 μg / $495

CREB1 / CREB Antibody (Ser133)

Brand

Leading Biology

Catalog Number

APR02401G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CREB1 / CREB Antibody (Ser133).

Molecular Weight

37kDa

Cellular Localization

Antigen Cellular Localization: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083}

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Amino acids surrounding Ser 133 of human CREB1

GeneID

UniProt ID

Function

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

Summary

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (10 μg/ml), WB (1:500-1:1000),

Images

Western blot of extracts from 293, HT29 and HeLa cells using CREB(Ab-133) antibody.

Anti-CREB1 / CREB antibody IHC of human skin.

Specification

Quantity

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