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TIRAP Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR02385G 50 μg / $495

TIRAP Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR02385G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TIRAP Antibody (C-Terminus).

Molecular Weight

24kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cell membrane. Membrane. Note=Colocalizes with DAB2IP at the plasma membrane

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

peptide corresponding to 15 amino acids near the C-terminus of mouse TIRAP

Symbol

MAL

GeneID

UniProt ID

Function

Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.

Summary

Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (5 μg/ml), WB (0.5-2 μg/ml),

Images

Anti-TIRAP antibody IHC of human heart.

Anti-TIRAP antibody IHC of human kidney.

Specification

Quantity

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