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TIRAP Antibody

Catalog # Availability Size / Price Inquiry
APR02279G 50 μg / $495

TIRAP Antibody

Brand

Leading Biology

Catalog Number

APR02279G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TIRAP Antibody.

Molecular Weight

24kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cell membrane. Membrane. Note=Colocalizes with DAB2IP at the plasma membrane

Host

Rabbit

Species Reactivity

Human

Target

peptide corresponding to amino acids near the middle of human TIRAP

Symbol

MAL

GeneID

UniProt ID

Function

Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.

Summary

Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF

Dilution

IHC-P (5 μg/ml), WB (4 μg/ml),

Images

Immunofluorescence of TIRAP in Human Heart cells with TIRAP antibody at 20 ug/ml.

Specification

Quantity

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