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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CARD8 / Cardinal / TUCAN Antibody (C-Terminus)

CARD8 / Cardinal / TUCAN Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR02244G 50 μg / $495

CARD8 / Cardinal / TUCAN Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR02244G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CARD8 / Cardinal / TUCAN Antibody (C-Terminus).

Molecular Weight

49kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus

Host

Rabbit

Species Reactivity

Human

Target

synthetic peptide corresponding to amino acids at the C-terminus of human CARD8

Symbol

KIAA0955, NDPP1

GeneID

UniProt ID

Function

Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.

Summary

Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, ICC

Dilution

IHC-P (5 μg/ml), WB (2 μg/ml),

Images

Immunocytochemistry of CARD8 in K562 cells with CARD8 antibody at 10 ug/ml.

Immunofluorescence of CARD8 in K562 cells with CARD8 antibody at 20 ug/ml.

Anti-CARD8 antibody IHC of human spleen.

Specification

Quantity

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