> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PPP1R13L / iASPP Antibody (aa780-797)Brand |
Leading Biology | Catalog Number |
APR02220G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PPP1R13L / iASPP Antibody (aa780-797).
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Molecular Weight |
89kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic but also nuclear
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
Amino acids 780-797 of human iASPP (isoform 1) protein.
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Symbol |
IASPP, NKIP1, PPP1R13BL, RAI
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GeneID |
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UniProt ID |
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Function |
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
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Summary |
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Dilution |
ELISA (1:40000-1:160000), IHC-P (2.5 μg/ml), WB (1:1000-1:5000)
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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