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CCNL1 / Cyclin L1 Antibody

Catalog # Availability Size / Price Inquiry
APR02180G 50 μg / $495

CCNL1 / Cyclin L1 Antibody

Brand

Leading Biology

Catalog Number

APR02180G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CCNL1 / Cyclin L1 Antibody.

Molecular Weight

60kDa

Cellular Localization

Antigen Cellular Localization: Nucleus speckle. Note=More specifically found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Synthetic construct consisting of full length Human Cyclin L1b protein.

GeneID

UniProt ID

Function

Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.

Summary

Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E, IP

Dilution

ELISA (1:5000-1:20000), IHC-P (10 μg/ml), WB (1:1000-1:5000)

Images

Anti-CCNL1 / Cyclin L1 antibody IHC of human skeletal muscle.

Specification

Quantity

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