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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > RARB / RAR Beta Antibody (C-Terminus)

RARB / RAR Beta Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR02049G 50 μg / $495

RARB / RAR Beta Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR02049G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RARB / RAR Beta Antibody (C-Terminus).

Molecular Weight

50kDa

Cellular Localization

Antigen Cellular Localization: Isoform Beta-1: Nucleus. Isoform Beta-4: Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Monkey, Pig, Horse

Target

Human RARB. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Symbol

HAP, NR1B2

GeneID

UniProt ID

Function

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.

Summary

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, E

Dilution

IHC-P (10 μg/ml)

Images

Anti-RARB antibody APR02049G IHC of human intermediate trophoblasts.

Specification

Quantity

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