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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GRM5 / MGLUR5 Antibody (N-Terminus)

GRM5 / MGLUR5 Antibody (N-Terminus)

Catalog # Availability Size / Price Inquiry
APR01943G 50 μg / $495

GRM5 / MGLUR5 Antibody (N-Terminus)

Brand

Leading Biology

Catalog Number

APR01943G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRM5 / MGLUR5 Antibody (N-Terminus).

Molecular Weight

132kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}; Multi-pass membrane protein {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}

Host

Rabbit

Species Reactivity

Human, Mouse, Rabbit, Hamster, Monkey, Pig, Chicken, Horse, Bovine, Dog

Target

Human GRM5 / MGLUR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Symbol

GPRC1E, MGLUR5

GeneID

UniProt ID

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.

Summary

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P

Dilution

IHC-P (5.6 μg/ml)

Images

Anti-GRM5 / MGLUR5 antibody APR01943G IHC of human colon, myenteric plexus.

Specification

Quantity

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