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CRABP2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR06936G 100 μl / $495

CRABP2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR06936G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRABP2 Antibody (C-term).

Molecular Weight

H=16;M=16;R=16 KDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Endoplasmic reticulum. Nucleus. Note=Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus

Host

Rabbit

Species Reactivity

Human

Immunogen

102-136 aa

Target

This CRABP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-136 amino acids from the C-terminal region of human CRABP2.

GeneID

UniProt ID

Function

Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.

Summary

A number of specific carrier proteins for members of the vitamin A family have been discovered. Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. The inducibility of the CRABP2 gene suggests that this isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. It has been postulated that the CRABP2 gene is transcriptionally regulated by a newly synthesized regulatory protein. [provided by RefSeq].

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~1:1000

Images

All lanes : Anti-CRABP2 Antibody (C-term) at 1:1000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: MDA-MB-453 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 16 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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