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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > RRAD (aa36-48) Antibody (internal region)

RRAD (aa36-48) Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APG00807G 0.1mg / $495

RRAD (aa36-48) Antibody (internal region)

Brand

Leading Biology

Catalog Number

APG00807G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RRAD (aa36-48) Antibody (internal region).

Molecular Weight

33245 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane.

Host

Goat

Species Reactivity

Mouse

Isotype

IgG

Symbol

RAD

GeneID

UniProt ID

Function

May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.

Summary

Reported variants represent identical protein: NP_004156.1, NP_001122322.1

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

A): APG00807G (0.5 μg/ml) staining of HEK293 lysates overexpressing several HA-tagged Mouse GTPases, including Rrad (10 μg protein in RIPA buffer) and compared with an HA-specific antibody. B): APG00807G (0.5 μg/ml) staining of WT and KO lysates of Mouse Heart (100 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Data provided by Prof. D Andres, University of Kentucky College of Medicine, USA.

Specification

Quantity

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