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IRF4 Antibody (C-Term)

Catalog # Availability Size / Price Inquiry
APG00796G 0.1mg / $495

IRF4 Antibody (C-Term)

Brand

Leading Biology

Catalog Number

APG00796G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IRF4 Antibody (C-Term).

Molecular Weight

51772 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

MUM1

GeneID

UniProt ID

Function

Transcriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

APG00796G (0.5 μg/ml) staining of Jurkat lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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