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CP110 Antibody (N-Term)

Catalog # Availability Size / Price Inquiry
APG00792G 0.1mg / $495

CP110 Antibody (N-Term)

Brand

Leading Biology

Catalog Number

APG00792G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CP110 Antibody (N-Term).

Molecular Weight

113424 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Recruited early and then associates with the growing distal tips. Recruited to the mother centriole by KIF24. Removed from centrioles by TTBK2, leading to initiation of ciliogenesis

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

CEP110, CP110, KIAA0419

GeneID

UniProt ID

Function

Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.

Summary

This antibody is expected to recognize both reported isoforms (NP_001185951.1; NP_055526.3).

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

APG00792G (1 μg/ml) staining of Human Testis lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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