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BTBD7 Antibody (N-Term)

Catalog # Availability Size / Price Inquiry
APG00731G 0.1mg / $495

BTBD7 Antibody (N-Term)

Brand

Leading Biology

Catalog Number

APG00731G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BTBD7 Antibody (N-Term).

Molecular Weight

126368 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Goat

Species Reactivity

Mouse

Isotype

IgG

Symbol

KIAA1525

GeneID

UniProt ID

Function

Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E- cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity).

Summary

This antibody is expected to recognize both reported isoforms (NP_001002860.2; NP_060637.1).

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

MDCK overexpressing Mouse Btbd7 (third lane) and probed with APG00731G (mock transfection in first lane, full construct chemically suppressed in second lane).

Specification

Quantity

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