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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CIAS1 / cryopyrin ( C Terminus) Antibody (C-Term)

CIAS1 / cryopyrin ( C Terminus) Antibody (C-Term)

Catalog # Availability Size / Price Inquiry
APG00389G 0.1mg / $495

CIAS1 / cryopyrin ( C Terminus) Antibody (C-Term)

Brand

Leading Biology

Catalog Number

APG00389G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CIAS1 / cryopyrin ( C Terminus) Antibody (C-Term).

Molecular Weight

118173 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

C1orf7, CIAS1, NALP3, PYPAF1

GeneID

UniProt ID

Function

May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.

Summary

Variants (NP_001073289.1; NP_004886.3) encode the same isoform.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

FC, E

Images

Specification

Quantity

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