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Goat Anti-TREML1 Antibody

Catalog # Availability Size / Price Inquiry
APG00369G 0.1mg / $495

Goat Anti-TREML1 Antibody

Brand

Leading Biology

Catalog Number

APG00369G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-TREML1 Antibody.

Molecular Weight

32679 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Sequestered in cytoplasmic vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

TLT1

GeneID

UniProt ID

Function

Cell surface receptor that may play a role in the innate and adaptive immune response.

Summary

TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 [PubMed 12645956]; Barrow et al., 2004 [PubMed 15128762]).

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

APG00369G staining (0.5 μg/ml) of Human Bone Marrow lysate (RIPA buffer, 35 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Specification

Quantity

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