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Goat Anti-USP11 / UHX1 Antibody

Catalog # Availability Size / Price Inquiry
APG00359G 0.1mg / $495

Goat Anti-USP11 / UHX1 Antibody

Brand

Leading Biology

Catalog Number

APG00359G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-USP11 / UHX1 Antibody.

Molecular Weight

109817 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Predominantly nuclear. Associates with chromatin

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

UHX1

GeneID

UniProt ID

Function

Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.

Summary

Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

APG00359G staining (1 μg/ml) of Jurkat lysate (RIPA buffer, 30 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Specification

Quantity

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