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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-CDCP1 (isoform 1: C term) Antibody

Goat Anti-CDCP1 (isoform 1: C term) Antibody

Catalog # Availability Size / Price Inquiry
APG00069G 0.1mg / $495

Goat Anti-CDCP1 (isoform 1: C term) Antibody

Brand

Leading Biology

Catalog Number

APG00069G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-CDCP1 (isoform 1: C term) Antibody.

Molecular Weight

92932 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cell membrane; Single-pass membrane protein. Note=Shedding may also lead to a soluble peptide

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

TRASK

GeneID

UniProt ID

Function

May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.

Summary

The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, IP, E

Images

APG00069G (1 μg/ml) staining of Human Colon lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

HEK293 overexpressing CDCP1 (RC220633) and probed with APG00069G (mock transfection in first lane), tested by Origene.

Specification

Quantity

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