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Goat Anti-BERP / RNF22 Antibody

Catalog # Availability Size / Price Inquiry
APG00047G  In Stock 0.1mg / $495

Goat Anti-BERP / RNF22 Antibody

Brand

Leading Biology

Catalog Number

APG00047G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-BERP / RNF22 Antibody.

Molecular Weight

80830 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Early endosome

Host

Goat

Species Reactivity

Mouse

Isotype

IgG

Symbol

BERP, RNF22, RNF97

GeneID

UniProt ID

Function

Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.

Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

APG00047G staining (0.05 μg/ml) of Mouse Brain lysate (RIPA buffer, 30 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

HEK293 overexpressing TRIM3 (RC211928) and probed with APG00047G (mock transfection in first lane), tested by Origene.

Specification

Quantity

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