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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > UBE2L3 antibody - C-terminal region

UBE2L3 antibody - C-terminal region

Catalog # Availability Size / Price Inquiry
APR00872G 100 μg / $495

UBE2L3 antibody - C-terminal region

Brand

Leading Biology

Catalog Number

APR00872G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UBE2L3 antibody - C-terminal region.

Molecular Weight

75kDa

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog

Symbol

UBCE7, UBCH7

GeneID

UniProt ID

Function

Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PARK2 and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down- regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Images

Human Intestine

WB Suggested Anti-UBE2L3 Antibody Titration: 1.25μg/ml Positive Control: Jurkat cell lysateThere is BioGPS gene expression data showing that UBE2L3 is expressed in Jurkat

Specification

Quantity

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