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AdipoR1 Antibody

Catalog # Availability Size / Price Inquiry
APR00228G 100 μg / $495

AdipoR1 Antibody

Brand

Leading Biology

Catalog Number

APR00228G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AdipoR1 Antibody.

Molecular Weight

42366 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein. Note=Localized to the cell membrane and intracellular organelles.

Host

Rabbit

Species Reactivity

Mouse

Target

AdipoR1

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.

Summary

The adiponectin receptors, ADIPOR1 and ADIPOR2 are receptors for globular and full-length adiponectin. These receptors mediate the increase of AMPK and PPAR-α ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

Antibody. Western blot analysis of AdipoR1 with 3T3 cell lysate.

Specification

Quantity

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