> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Dectin-1 AntibodyBrand |
Leading Biology | Catalog Number |
APR00218G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Dectin-1 Antibody.
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Molecular Weight |
27627 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Single- pass type II membrane protein Isoform 6: Cytoplasm.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
Dectin-1
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Isotype |
Rabbit IgG
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Symbol |
BGR, CLECSF12, DECTIN1
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GeneID |
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UniProt ID |
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Function |
Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).
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Summary |
Dectin-1also known as beta-glucan receptor is a small type II transmembrane receptor containing lectin-like carbohydrate recognition domain. Dectin-1 plays a role in beta-glucan dependant, nonopsonic recognition of zymosan by primary macropahge. Dectin-1 is expressed on macrophages and neutrophils and on some dendritic cells subpopulation.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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