> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GPVI AntibodyBrand |
Leading Biology | Catalog Number |
APR00208G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GPVI Antibody.
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Molecular Weight |
36866 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Cell membrane; Single-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
GPV
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Isotype |
Rabbit IgG
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GeneID |
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UniProt ID |
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Function |
Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2.
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Summary |
Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets. GPVI plays an important role in platelet procoagulant activity and the formation of thrombin and fibrin.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Images |
Western blot analysis of GPVI expression in Jurkat cell lysate (Lane 1, 2). |
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Specification |
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Quantity |
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Leading Biology Inc.
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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