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GPVI Antibody

Catalog # Availability Size / Price Inquiry
APR00208G 100 μg / $495

GPVI Antibody

Brand

Leading Biology

Catalog Number

APR00208G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GPVI Antibody.

Molecular Weight

36866 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cell membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Target

GPV

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2.

Summary

Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets. GPVI plays an important role in platelet procoagulant activity and the formation of thrombin and fibrin.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

Western blot analysis of GPVI expression in Jurkat cell lysate (Lane 1, 2).

Specification

Quantity

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