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Galectin-1 Antibody

Catalog # Availability Size / Price Inquiry
APR00144G 100 μg / $495

Galectin-1 Antibody

Brand

Leading Biology

Catalog Number

APR00144G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Galectin-1 Antibody.

Molecular Weight

14716 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix

Host

Rabbit

Species Reactivity

Human

Target

Galectin 1

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.

Summary

Galectins are a family of soluble β-galactoside-binding animal lectins that modulate cell-to-cell and cell-to-ECM interactions, as well as apoptosis. Galectin-1 has the ability to induce apoptosis of activated T-cells and T-leukaemia cell lines. Other activities include cell differentiation and inhibition activity of CD45 protein phosphatase activity. Galectin also binds beta-galactoside as well as CD45, CD3 and CD4. Human Galectin is a 14.5 kDa protein consisting of 134 amino acid residues.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Images

Specification

Quantity

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