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FAF1 Antibody

Catalog # Availability Size / Price Inquiry
APR00073G 100 μg / $495

FAF1 Antibody

Brand

Leading Biology

Catalog Number

APR00073G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FAF1 Antibody.

Molecular Weight

73954 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

FAF1

Isotype

Rabbit IgG

Symbol

UBXD12, UBXN3A

GeneID

UniProt ID

Function

Potentiates but cannot initiate FAS-induced apoptosis.

Summary

FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. When transiently expressed in T cells, FAF1 potentiates Fas-induced apoptosis. In contrast to TRADD, FADD, and RIP, FAF1 lacks a DDH (Death domain homologous region) and cannot induce apoptosis independent of Fas activation.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, IP

Images

Specification

Quantity

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