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Profilin-1 Antibody

Catalog # Availability Size / Price Inquiry
APR00064G 100 μg / $495

Profilin-1 Antibody

Brand

Leading Biology

Catalog Number

APR00064G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Profilin-1 Antibody.

Molecular Weight

14957 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Bovine

Target

Profilin-1

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR (By similarity).

Summary

Profilin is a protein which maintains and shapes cytoskeleton by binding to actin. Profilin 1 has function in breast cancer cell motility, radial migration and glial cell adhesion.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Images

Western blot analysis of Profilin 1 using lysate From Jurkat cells (Lane 1), 3T3 cells (Lane 2) and rat kidney tissue lysate (Lane 3).

Specification

Quantity

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