> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > BAK1 AntibodyBrand |
Leading Biology | Catalog Number |
APR00005G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BAK1 Antibody.
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Molecular Weight |
23409 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion membrane; Single-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
Bak1
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Isotype |
Rabbit IgG
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Symbol |
BAK, BCL2L7, CDN1
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GeneID |
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UniProt ID |
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Function |
In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
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Summary |
Bak is a homolog of apoptosis inhibitor Bcl-2. Bak is a member of the Bcl-2 family of proteins and contains Bcl-2 homology region (BH-) 1, 2 and 3. Unlike Bcl-2, Bak promotes cell death and counteracts the anti-apoptotic effect of Bcl-2. The immunoaffinity purified antibody detects a 30 kDa band, corresponding to the expected molecular weight of Bak on SDS-PAGE immunoblots.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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