> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GRB2 Antibody (Y209)Brand |
Leading Biology | Catalog Number |
APR05738G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GRB2 Antibody (Y209).
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Molecular Weight |
25206 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Endosome. Golgi apparatus
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
187-216 aa
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Target |
This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from human GRB2.
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Isotype |
Rabbit Ig
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Symbol |
ASH
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GeneID |
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UniProt ID |
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Function |
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
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Summary |
GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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