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STEA2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR05658G 100 μl / $495

STEA2 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR05658G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STEA2 Antibody (Center).

Molecular Weight

56056 Da

Cellular Localization

Antigen Cellular Localization: Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

226-253 aa

Target

This STEAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the Central region of human STEAP2.

Isotype

Rabbit Ig

Symbol

PCANAP1, STAMP1

GeneID

UniProt ID

Function

Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).

Summary

This gene is a member of the STEAP family and encodes amulti-pass membrane protein that localizes to the Golgi complex,the plasma membrane, and the vesicular tubular structures in thecytosol. A highly similar protein in mouse has both ferrireductaseand cupric reductase activity, and stimulates the cellular uptakeof both iron and copper in vitro. Increased transcriptionalexpression of the human gene is associated with prostate cancerprogression. Alternate transcriptional splice variants, encodingdifferent isoforms, have been characterized.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:500 IHC-P~~1:50~100 FC~~1:10~50

Images

Western blot analysis of lysates from 293, HepG2 cell line, mouse spleen tissue lysate (from left to right), using STEAP2 Antibody (Center)(APR05658G). APR05658G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

Western blot analysis of extracts from 293 (lanes 1 and 2),HepG2 (lanes 3 and 4)cell line and mouse spleen (lanes 5 and 6)tissue lysate: 1, 3, 5. using STEAP2 Antibody (Center)( APR05658G), (1:500). 2, 4, 6. using STEAP2 Antibody (Center), preincubated with the control peptide antigen.

STEAP2 Antibody (Center) (Cat. APR05658G) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STEAP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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