> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HAVCR2 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR04502G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HAVCR2 Antibody (Center).
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Molecular Weight |
33394 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
167-194 aa
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Target |
This HAVCR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-194 amino acids from the Central region of human HAVCR2.
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Isotype |
Rabbit Ig
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Symbol |
TIM3, TIMD3
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GeneID |
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UniProt ID |
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Function |
Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.
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Summary |
CD4 (MIM 186940)-positive T helper lymphocytes can bedivided into types 1 (Th1) and 2 (Th2) on the basis of theircytokine secretion patterns. Th1 cells and their associatedcytokines are involved in cell-mediated immunity to intracellularpathogens and delayed-type hypersensitivity reactions, whereas Th2cells are involved in the control of extracellular helminthicinfections and the promotion of atopic and allergic diseases. The 2types of cells also cross-regulate the functions of the other. TIM3is a Th1-specific cell surface protein that regulates macrophageactivation and enhances the severity of experimental autoimmuneencephalomyelitis in mice.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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