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Mouse Camkk2 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR04046G 100 μl / $495

Mouse Camkk2 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR04046G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Camkk2 Antibody (N-term).

Molecular Weight

64618 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Cell projection. Note=Predominantly nuclear in unstimulated cells. Found in the cytoplasm and neurites after forskolin induction.

Host

Rabbit

Species Reactivity

Mouse

Immunogen

43-71 aa

Target

This Mouse Camkk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the N-terminal region of mouse Camkk2.

Isotype

Rabbit Ig

Symbol

Kiaa0787

GeneID

UniProt ID

Function

Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK4 and CAMK1D (By similarity). Efficiently phosphorylates 5'-AMP- activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). May play a role in neurite growth. Isoform 2 may promote neurite elongation, while isoform 1 may promoter neurite branching (By similarity). May be involved in hippocampal activation of CREB1.

Summary

Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK4 and CAMK1D (By similarity). Seems to be involved in hippocampal activation of CREB1.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Mouse Camkk2 Antibody (N-term) (Cat. APR04046G) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Camkk2 antibody detected the Camkk2 protein (arrow).

Western blot analysis of lysates from U-87 MG cell line , human brain and rat cerebellum tissue lysate(from left to right), using Mouse Camkk2 Antibody (N-term)(APR04046G). APR04046G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Specification

Quantity

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