> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > IL1RL2 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR03811G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL1RL2 Antibody (Center).
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Molecular Weight |
65405 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
257-286 aa
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Target |
This IL1RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-286 amino acids from the Central region of human IL1RL2.
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Isotype |
Rabbit Ig
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Symbol |
IL1RRP2
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GeneID |
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UniProt ID |
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Function |
Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL- 23/IL-17/IL-22 pathway.
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Summary |
The protein encoded by this gene is a member of theinterleukin 1 receptor family. An experiment with transient geneexpression demonstrated that this receptor was incapable of bindingto interleukin 1 alpha and interleukin 1 beta with high affinity.This gene and four other interleukin 1 receptor family genes,including interleukin 1 receptor, type I (IL1R1), interleukin 1receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1),and interleukin 18 receptor 1 (IL18R1), form a cytokine receptorgene cluster in a region mapped to chromosome 2q12. [provided byRefSeq].
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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