> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > POU6F2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03669G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality POU6F2 Antibody (N-term).
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Molecular Weight |
73265 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
34-61 aa
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Target |
This POU6F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human POU6F2.
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Isotype |
Rabbit Ig
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Symbol |
RPF1
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GeneID |
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UniProt ID |
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Function |
Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA.
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Summary |
This gene encodes a member of the POU protein familycharacterized by the presence of a bipartite DNA binding domain,consisting of a POU-specific domain and a homeodomain, separated bya variable polylinker. The DNA binding domain may bind to DNA asmonomers or as homo- and/or heterodimers, in a sequence-specificmanner. The POU family members are transcriptional regulators, manyof which are known to control cell type-specific differentiationpathways. This gene is a tumor suppressor involved in Wilms tumor(WT) predisposition. Alternatively spliced transcript variantsencoding distinct isoforms have been found for this gene.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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