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HMMR Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03616G 100 μl / $495

HMMR Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03616G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HMMR Antibody (C-term).

Molecular Weight

84100 Da

Cellular Localization

Antigen Cellular Localization: Cell surface. Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

668-697 aa

Target

This HMMR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-697 amino acids from the C-terminal region of human HMMR.

Isotype

Rabbit Ig

Symbol

IHABP, RHAMM

GeneID

UniProt ID

Function

Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity.

Summary

The protein encoded by this gene is involved in cellmotility. It is expressed in breast tissue and together with otherproteins, it forms a complex with BRCA1 and BRCA2, thus ispotentially associated with higher risk of breast cancer.Alternatively spliced transcript variants encoding differentisoforms have been noted for this gene.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Images

All lanes : Anti-HMMR Antibody (C-term) at 1:2000 dilution Lane 1: K562 whole cell lysates Lane 2: LNCaP whole cell lysates Lane 3: HL-60 whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 84 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

HMMR Antibody (C-term) (Cat. APR03616G) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the HMMR antibody detected the HMMR protein (arrow).

HMMR Antibody (C-term) (Cat. APR03616G)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HMMR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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