> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TBX6 Antibody (Center W158)Brand |
Leading Biology | Catalog Number |
APR03597G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TBX6 Antibody (Center W158).
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Molecular Weight |
47045 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00201}
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
143-172 aa
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Target |
This TBX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of human TBX6.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity).
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Summary |
This gene is a member of a phylogenetically conservedfamily of genes that share a common DNA-binding domain, the T-box.T-box genes encode transcription factors involved in the regulationof developmental processes. Knockout studies in mice indicate thatthis gene is important for specification of paraxial mesodermstructures.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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