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Cyclin G1 Antibody

Catalog # Availability Size / Price Inquiry
APR00380G 50 μl / $495

Cyclin G1 Antibody

Brand

Leading Biology

Catalog Number

APR00380G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cyclin G1 Antibody.

Molecular Weight

34074 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Note=DNA replication foci after DNA damage

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Pig, Bovine

Target

Cyclin G1

Isotype

Rabbit IgG

Symbol

CCNG, CYCG1

GeneID

UniProt ID

Function

May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).

Summary

Cyclin-G1 (CCNG1) belongs to the cyclin family and contains the cyclin box. CCNG1 may have a part in growth regulation and is associated with G2/M phase arrest in response to DNA damage. CCNG1 may be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation. The CCNG1 protein lacks the protein destabilizing (PEST) sequence which is present in other family members.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Images

Immunohistochemical analysis of Cyclin G1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Western blot analysis of Cyclin G1 expression in DLD (A), Jurkat (B), mouse liver (C), rat liver (D) whole cell lysates

Specification

Quantity

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