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NSE4A Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR06212G 100 μl / $495

NSE4A Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR06212G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NSE4A Antibody (N-term).

Molecular Weight

44301 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Chromosome, telomere

Host

Rabbit

Species Reactivity

Human

Immunogen

29-57 aa

Target

This NSE4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human NSE4A.

Isotype

Rabbit Ig

Symbol

C10orf86

GeneID

UniProt ID

Function

Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Western blot analysis of NSE4A Antibody (N-term) (Cat. APR06212G) in WiDr cell line lysates (35ug/lane). NSE4A (arrow) was detected using the purified Pab.

Specification

Quantity

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