> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > hPFTK1-M1 AntibodyBrand |
Leading Biology | Catalog Number |
APR06196G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality hPFTK1-M1 Antibody.
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Molecular Weight |
53057 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Note=Recruited to the cell membrane by CCNY
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
1-30 aa
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Target |
This hPFTK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human hPFTK1.
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Isotype |
Rabbit Ig
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Symbol |
KIAA0834, PFTK1
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GeneID |
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UniProt ID |
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Function |
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
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Summary |
PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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