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REG3A Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR06151G 100 μl / $495

REG3A Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR06151G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality REG3A Antibody (N-term).

Molecular Weight

19395 Da

Cellular Localization

Antigen Cellular Localization: Secreted. Note=Found in the apical region of pancreatic acinar cells

Host

Rabbit

Species Reactivity

Human

Immunogen

12-39 aa

Target

This REG3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human REG3A.

Isotype

Rabbit Ig

Symbol

HIP, PAP, PAP1

GeneID

UniProt ID

Function

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.

Summary

REG3A encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this protein is observed during pancreatic inflammation and liver carcinogenesis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Images

Western blot analysis of lysate from RPMI-8226 cell line, using REG3A Antibody (N-term)(Cat. APR06151G). APR06151G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

REG3A Antibody (N-term) (Cat. APR06151G) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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