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DPP10 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR06134G 100 μl / $495

DPP10 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR06134G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DPP10 Antibody (Center).

Molecular Weight

90888 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

150-177 aa

Target

This DPP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-177 amino acids from the Central region of human DPP10.

Isotype

Rabbit Ig

Symbol

DPRP3, KIAA1492

GeneID

UniProt ID

Function

Has no dipeptidyl aminopeptidase activity. May modulate cell surface expression and activity of the potassium channels KCND1 and KCND2.

Summary

DPP10 is a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Images

Western blot analysis of DPP10 Antibody (Center) (Cat. APR06134G) in Y79, MDA-MB231 cell line and mouse liver, brain tissue lysates (35ug/lane). DPP10 (arrow) was detected using the purified Pab.

DPP10 Antibody (Center) (Cat. APR06134G) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DPP10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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